The Gadsden flag, offering a rattlesnake and the phrase "Don't Tread on Me

https://damienqulw756.laurelcurrent.com/posts/quality-matters-why-you-should-invest-in-authentic-civil-war-flags-2

The Gadsden flag, providing a rattlesnake and the phrase "Don't Tread on Me," was adopted via some Confederate contraptions as a symbol of resistance opposed to perceived oppression.